MutationView : An Integrated Knowledge Base for Mutations and Polymorphisms in Human Disease Genes - Automatical Extraction of Disease-Associated Knowledge -
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چکیده
One of the important purposes of genome research is to elucidate the nature of genes responsible for monogenic as well as multigenic diseases. In order to better understand correlation between disease and genetic diversity, we developed an integrated database system MutationView, which at present mainly deals with monogenic diseases (http://mutview.dmb.med.keio.ac.jp). MutationView is the system which can search, display and analyze the mutation data with graphical environment.
منابع مشابه
KMDB / MutationView : An Integrated Knowledge Base for Mutations and Polymorphisms in Human Disease Genes – Data Expansion and Further Functional Development –
More than 1000 disease-causing genes have been reported. Databases for mutations in these diseasecausing genes are indispensable for the diagnostics, therapeutics and basic research of the diseases. At present, mutation data are maintained as individual Locus-specific Databases (LSDBs) for some 200 diseases and therefore more comprehensive database system with common graphical user-interface is...
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تاریخ انتشار 2003